You Are The Cure!
YOU ARE THE CURE!
Your Guide to Alzheimer's Clinical Trials
Deciding to participate in a clinical trial is a significant personal choice. This guide provides clear, compassionate answers to help you make an informed decision on your journey.
Start ExploringWhat Are Clinical Trials?
This section explains the fundamentals of clinical research. Understanding the different types of studies and the structured phases of a trial can help set clear expectations about what participation involves and why it is so crucial for medical progress in Alzheimer's disease.
Two Main Types of Research
Observational Studies
Researchers observe participants to understand disease progression and identify risk factors without administering new treatments. Your contribution helps build the foundational knowledge for future breakthroughs.
Interventional Trials
Researchers test new treatments, like drugs or lifestyle changes, to see if they are safe and effective. These trials offer the possibility of accessing a new therapy before it's widely available.
Trial Participant Scale
The Four Phases of a Clinical Trial
1
2
3
4
The Participation Journey
Here, we outline what you can typically expect if you decide to participate in a trial. This includes common eligibility criteria that researchers look for and the types of tests and procedures you might undergo. This information is designed to give you a clearer picture of the commitment and process involved.
Common Eligibility Criteria
Each study has specific requirements. Here are some common factors researchers consider. This is a general guide and not a screening tool.
- ✓Age Range: Typically between 50 and 89, but this varies significantly by study.
- ✓Diagnosis: Often focuses on Mild Cognitive Impairment (MCI) or mild Alzheimer's dementia.
- ✓Cognitive Status: A baseline score on tests like the MMSE is usually required.
- ✓Study Partner: Most trials require a reliable partner who can attend visits and provide insights.
- ✓Biomarkers: Many modern trials require evidence of amyloid or tau proteins from PET scans or spinal fluid.
What to Expect: Tests & Procedures
Click on an icon to learn more about the common tests and procedures you might encounter during a trial.
Your Safety, Rights & Well-being
Participant safety is the highest priority in any clinical trial. This section covers the robust systems in place to protect you, your fundamental rights as a participant, and practical considerations like costs and privacy. Your well-being is protected at every step.
🛡️
How Am I Protected?
Independent committees like Institutional Review Boards (IRBs) and Data Safety Monitoring Committees (DSMCs) review and monitor studies to ensure they are ethical and safe.
⚖️
What Are My Rights?
You have the absolute right to withdraw from a study at any time, for any reason. Your personal health information is also kept private and confidential under strict laws like HIPAA.
💰
Are There Costs?
No, all study-related procedures and treatments are paid for by the sponsor. You may also be compensated for your time and reimbursed for expenses like travel and parking.
Finding a Trial & Key Questions
If you are considering participation, it's important to know where to find information and what to ask. This section provides resources for finding ongoing trials and a list of key questions to discuss with the research team to ensure you are fully informed.
Key Questions to Ask
Where to Find Trials
-
Talk to Your Doctor
Your primary care physician or neurologist is the best starting point for a referral.
-
National Registries
Online databases provide comprehensive, searchable lists of trials.
-
Alzheimer's Association
Their free TrialMatch® service connects you with studies that fit your profile.
TrialMatch®