Enhancing Alzheimer's Drug Development: Strategies for Success

Alzheimer's Disease (AD) remains a formidable challenge in modern medicine, with drug discovery and development efforts historically plagued by high failure rates. The staggering statistic that over 200 AD drug candidates have failed to date underscores the complexity and difficulties in tackling this neurodegenerative disease. This essay will critically analyze the factors contributing to this high failure rate and explore potential strategies for increasing success in future AD drug development, primarily drawing insights from Robert E. Becker and Nigel H. Greig's 2012 paper, "Increasing the success rate for Alzheimer's disease drug discovery and development."