Groundbreaking 2026 research reveals structural brain changes precede amyloid plaques by 7+ years, transforming early detection, atypical Alzheimer's care, and targeted treatments.

For years, we have known that people with early-stage Alzheimer’s often struggle to get a good night's rest. For a long time, scientists thought this was simply because of "plaques"—sticky protein buildups called amyloid—clogging up the brain. However, new research from the University of Kentucky suggests the problem isn't just the plaques