EyePoint Pharmaceuticals has successfully concluded Phase III enrollment for Duravyu (EYP-1901), a groundbreaking sustained-release therapy for wet Age-related Macular Degeneration (wet AMD). With over 400 subjects across the pivotal LUCIA and LUGANO trials

Breaking News: Get the full, transparent details on why Viatris's investigational MR-139 (pimecrolimus 0.3%) ophthalmic ointment for blepharitis failed its Phase III trial. Discover how the therapy did not meet its primary endpoint of complete resolution of debris after six weeks of twice-daily dosing.

Discover encouraging results from BioAtla's Phase I trial of BA3182 for heavily pretreated metastatic adenocarcinoma. This innovative dual-conditionally active biologic (CAB) therapy, designed to minimize off-target toxicities, has demonstrated a reassuring safety profile with predominantly low-grade and manageable adverse events. The study has observed objective tumour size decreases in five subjects across various cancer types, including two colorectal carcinoma subjects with impressive progression-free intervals of 11 and 14 months. With ongoing dose escalation, updated Phase I data are anticipated later this year, highlighting the potential of BA3182 as a new treatment option.

This study investigates the complex relationship between holding dialectical views on contradictions and psychological well-being, specifically examining depressive symptoms and life satisfaction. It explores the moderating roles of culture (European American vs. Asian American) and age, and the mediating role of mindfulness facets. Findings indicate that dialectical views are associated with increased depressive symptoms and lower life satisfaction primarily among younger European Americans,