Explore the frontiers of space pharmacology, analyzing profound knowledge gaps in drug pharmacokinetics and pharmacodynamics under extreme microgravity and radiation conditions. This research highlights the imperative for personalized medicine, innovative sampling methods (DUS/DBS), and enhanced pharmaceutical stability to safeguard astronaut health and optimize long-duration deep space missions to the Moon and Mars.

Embark on Intermountain Healthcare's inspiring journey towards health equity! Discover how they're uniting the power of data with a commitment to culture change to create a fairer healthcare experience for all. From using clever dashboards to uncover disparities to fostering brave conversations about systemic racism, see how Intermountain is taking essential first steps, learning along the way, to build a future where everyone can live their healthiest life. It's a testament to progress, one thoughtful step at a time!

Dementia, a broad term for a decline in mental ability severe enough to interfere with daily life, is a growing global health concern. As populations age, understanding the true scope of dementia becomes crucial for healthcare planning

This study investigates the complex relationship between holding dialectical views on contradictions and psychological well-being, specifically examining depressive symptoms and life satisfaction. It explores the moderating roles of culture (European American vs. Asian American) and age, and the mediating role of mindfulness facets. Findings indicate that dialectical views are associated with increased depressive symptoms and lower life satisfaction primarily among younger European Americans,

Did AI truly manipulate Reddit users without their knowledge? Dive into the explosive details of the "exceptionally challenging" fake news study by Swiss-based researchers, linked to the University of Zurich, that secretly deployed AI bots using Large Language Models (LLMs) to invent opinions and influence public discourse on r/changemyview. Unaware participants debated AI-composed viewpoints, stretching ethical boundaries "beyond breaking point". This controversial experiment, which failed to inform participants in advance, "provoked a storm of criticism" from the Reddit community, researchers, and international media. Discover why researchers "disobeyed the rules" of the platform and their subsequent "full and deeply felt apology," even as questions of "bad science is bad ethics" and potential data protection violations persist.

Discover the extensive applications of Artificial Intelligence (AI) in pharmaceutical and healthcare research. Learn how AI is used for drug discovery, disease diagnosis, including cancer and dementia, and personalized treatment. Explore AI's crucial role in clinical trials, aiding in design, patient selection, monitoring, and analysis, and its potential to uncover valuable insights hidden in clinical protocols. Find out how AI assists in forecasting epidemics and pandemics.

Learn how global crises, from Brexit and COVID-19 to cybersecurity threats and natural disasters, are challenging clinical trial teams. Discover how proactivity, flexibility, collaboration, and IRT technology are key to minimizing participant disruption and ensuring study continuity in turbulent times.

Explore the significant impact of medical errors in healthcare, estimated to cause tens of thousands of deaths annually in the U.S.. Understand how systemic issues and processes contribute to preventable harm. Learn why system redesign, informed by human factors and systems engineering, is crucial for avoiding injuries to patients and improving safety.

Trace the remarkable journey of patient empowerment over 25 years, from a passive role to an active partner, fueled by increased access to knowledge and technological advancements.

Learn how novel approaches to clinical trial design, including integrated models and adaptive methods, are addressing the high costs and inefficiency of traditional drug development, particularly in Phase II and III trials, to reduce attrition rates and increase productivity.

 PTSD is highly prevalent among US veterans. This study found that among older veterans, a PTSD diagnosis conferred a significantly increased risk of developing dementia, with rates higher throughout the follow-up period. This underscores the importance of screening and treatment for those with PTSD.

This research looks at how memory and thinking skills change in middle-aged Spanish people who don't have the brain changes usually seen in Alzheimer's disease. Scientists checked their brain fluid to confirm this. They used special methods to track these changes over time and created new ways to compare their scores that are more sensitive than regular tests. The results suggest these new methods might be slightly better at finding very early, subtle declines in memory, which could be a sign of preclinical Alzheimer's. This study hopes to provide doctors with another tool to help spot early changes that might lead to Alzheimer's later in life.

Explore the Hepatitis B global clinical trial landscape in 2025 with insights into novel therapies, ongoing research for a functional cure, emerging biomarkers, and investment trends from a new report by Novotech

Acquire knowledge concerning Alzheimer's disease diagnosis, prevailing symptomatic treatments, and ongoing research initiatives dedicated to early intervention strategies and therapeutic approaches targeting amyloid and tau proteins.

Explore the critical topic of minority engagement in US clinical research on the Glassbury Cares Podcast. We discuss the persistent challenges of lower participation rates among racial and ethnic minorities in clinical trials, including HIV research. Understand how distrust of the medical community and research, significantly influenced by historical events like the Tuskegee study, acts as a barrier. Learn about other impediments, such as accessibility issues, time commitments, language barriers, stigma, and limited knowledge. Discover facilitators that encourage participation, including altruism, perceived personal and community benefits, trust, culturally relevant services, and monetary compensation. We examine ethical considerations, the importance of justice, and strategies like community-based participatory research to build trust and address structural barriers